Can Macrolide Antibiotics Prevent Hospital Readmissions?

COPD Bundle to Prevent Hospital Readmissions and ED Visits.

Th e search for interventions to reduce avoidable readmissions aft er an exacerbation of COPD has attracted substantial attention aft er the Centers for Medicare & Medicaid Services included COPD exacerbations in its Hospital Readmissions Reduction Program. 1 We read with great interest the study by Jennings et al 2 in a recent issue of CHEST (May 2015) and applaud the authors for conducting a ...

The polyene macrolide antibiotics.

The mode of action of the polyene antibiotics is reviewed together with the effect of genetic and environmental factors on sensitive organisms. The future prospects of polyenes in the treatment of systemic mycoses are considered.

Hospital Readmissions for COPD: We Can Meet the Challenge.

Stereochemical problems in macrolide antibiotics.

Since 1950, well over fifty macrolides have been derived from various Actinomycetes in screening laboratories located at many corners of the world. Among the most intensely studied macrolides are those produced on a commercial scale (erythromycin, oleandomycin, tylosin, leucomycin and spiramycin) as well as examples of particular historical/scientific importance (Magnamycin, pikromycin, narbomy...

Macrolide antibiotics and pulmonary inflammation.

Many clinically effective therapeutic agents can exhibit localized and systemic effects that are manifestly different from their intended primary pharmacological mode of action. Macrolide antibiotics such as erythromycin and its derivatives are no exception. In addition to their antibacterial action, this class of antibiotics exhibits anti-inflammatory activity in a variety of airway diseases s...